Here's something different:
Most people have raved on and on and started multiple threads about their favourite p/u combos.
I want to hear about the 'hits and misses', in other words, pickup combinations that have been tried but just don't sound acceptable.
State your guitar type, i.e. strat, LP, superstrat etc.
State the guitar's wood
State whether fixed bridge, floyd rose, or traditional style trem etc etc.
And of course pickups in other positions.
Early this year, I thought I would replace the pickups on my Ibanez S-series (mahogany) for a Dimarzio Breed (n) and Dimarzio Evolution (b) I wanted the sweet fat tones of the Breed with the blazing rawness of the Evo in the bridge.
The breed was spot-on but the Evo was disappointing. The Floyd-trem made it sound thin and harsh. Strangely enough, it didn't sound mid-range full, but rather just very harsh. Currently debating changing to a custom-custom (b).
OK, your turn, guys.